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抗小鼠 CD4 单克隆抗体 FITC 偶联,流动验证 BES2307LAb

抗小鼠 CD4 单克隆抗体 FITC 偶联,流动验证 BES2307LAb

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抗小鼠 CD4 单克隆抗体 FITC 偶联,流动验证 BES2307LAb

货号BES2307LAb
产品名称抗小鼠 CD4 单克隆抗体 FITC 偶联,流动验证 
基因名CD4
抗体来源Rat
克隆Monoclonal
抗体亚型Rat
内容Phosphate-buffered aqueous solution, 0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.
浓度500 ug/ml
产品形态Liquid
保存条件12 months from date of receipt,-20℃ as supplied. 6 months 2 to 8℃ after reconstitution. Avoid repeated freezing and thawing.
背景资料This gene encodes a membrane glycoprotein of T lymphocytes that interacts with major histocompatibility complex class II antigenes and is also a receptor for the human immunodeficiency virus. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, and granulocytes. It is also expressed in specific regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene.
研究类别1. Ansari-Lari, M. A., Muzny, D. M., Lu, J., Lu, F., Lilley, C. E., Spanos, S., Malley, T., Gibbs, R. A. A gene-rich cluster between the CD4 and triosephosphate isomerase genes at human chromosome 12p13. Genome Res. 6: 314-326, 1996.2. Ben-Sasson, S. Z., Hu-Li, J., Quiel, J., Cauchetaux, S., Ratner, M., Shapira, I., Dinarello, C. A., Paul, W. E. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc. Nat. Acad. Sci. 106: 7119-7124, 2009.3. Buttini, M., Westland, C. E., Masliah, E., Yafeh, A. M., Wyss-Coray, T., Mucke, L. Novel role of human CD4 molecule identified in neurodegeneration. Nature Med. 4: 441-446, 1998.



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